Self-Reported Weather Sensitivity is Associated with Clinical Symptoms and Structural Abnormalities in Patients with Knee Osteoarthritis: A Cross-Sectional Study

IntroductionPatients with knee osteoarthritis (KOA) often complain about clinical symptoms affected by weather-related factors. The purpose of the present study was to use cross-sectional analysis determine whether weather sensitivity associated symptoms, as well structure abnormalities, in KOA patients.MethodsData from 80 participants were obtained Feng Hans Shi Effects on OA (FHS) study, an cohort initiated China 2015. each participant determined a self-reported questionnaire. following measurements used assess outcomes: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) for semi-quantitative Whole-Organ Magnetic Resonance Imaging Score (WORMS) cartilage defects marrow abnormalities magnetic resonance imaging (MRI). Chi-square Cochran–Armitage test trend regression evaluate associations between WOMAC WORMS patients.ResultsMost (57.5%) perceived affecting their knee-joint symptoms. After adjusting age, gender, body mass index (BMI), not only pain [OR = 3.3 (95% CI 1.1, 9.9), P 0.032], dysfunction 5.5 1.8, 16.8), 0.003], overall 10.2), 0.034], but also defect 3.1 8.5), 0.027] abnormality 3.0 8.1), 0.029].ConclusionsIn patients, structural abnormalities. Future longitudinal is warranted causal relationship.Infographic